Research Advances in Biomanufacturing of Nutritional Chemicals

Author:

WANG Nankai

School of Biotechnology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi 214122, China
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GONG Jinsong

School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, China
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SHI Jinsong

School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, China
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XU Zhenghong

School of Biotechnology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, Jiangnan University, Wuxi 214122, China
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摘要:

基于綠色生物制造合成營養(yǎng)化學(xué)品是實現(xiàn)可持續(xù)發(fā)展的重要保障，該領(lǐng)域的技術(shù)發(fā)展和應(yīng)用有望給食品、醫(yī)藥、化工及農(nóng)業(yè)等行業(yè)帶來顛覆性的技術(shù)變革。作者概述了生物信息學(xué)、基因組編輯技術(shù)、系統(tǒng)代謝工程策略以及酶工程技術(shù)等在營養(yǎng)化學(xué)品生物制造領(lǐng)域的應(yīng)用研究進展；簡述了功能糖類、氨基酸類、功能性脂質(zhì)類、維生素類和黃酮類營養(yǎng)化學(xué)品的生物制造方法，展望了營養(yǎng)化學(xué)品的生物制造未來及可能存在的挑戰(zhàn)，期待為提升綠色生物制造的競爭力提供參考。

Abstract:

The green biomanufacturing of nutritional chemicals is an important guarantee for sustainable development. The technological development and application of this field are expected to bring disruptive technological changes in food, pharmaceutical, chemical and agricultural industries. In this paper, we summarized the progress of bioinformatics, genome editing technology, system metabolic engineering strategy and enzyme engineering technology in the field of biomanufacturing of nutritional chemicals. Furthermore, the biological manufacturing methods of functional sugars, amino acids, functional lipids, vitamins and flavonoids were briefly described. Finally, the possible challenges in the future of biomanufacturing of nutrient chemicals were prospected. It is expected to provide a reference and support for promoting the competitiveness of green biomanufacturing.

王南凱,龔勁松,史勁松,許正宏.營養(yǎng)化學(xué)品的生物制造研究進展[J].食品與生物技術(shù)學(xué)報,2022,41(8):1-9.

WANG Nankai, GONG Jinsong, SHI Jinsong, XU Zhenghong. Research Advances in Biomanufacturing of Nutritional Chemicals[J]. Journal of Food Science and Biotechnology,2022,41(8):1-9.

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